ABCB4/MDR3 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human, Mouse
- Application:WB, IF/ICC
- Host:Rabbit
- Clonality:Polyclonal
- Target:ABCB4/MDR3
-
Brand:
CAT.NO. : ARA6660
RMB Please choose
RMB Please choose
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
Background
The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:2000 |
|
IF/ICC |
1:50 - 1:200 |
Overview
|
Immunogen |
Recombinant fusion protein of human MDR3. The exact sequence is proprietary. |
|
Purification Method |
The antibody was purified by immunogen affinity chromatography. |
|
Clone Type |
Polyclonal |
|
Product Form |
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
|
Gene Name |
ABCB4 |
|
Related Names |
MDR3; PGY3; Multidrug resistance protein 3; ATP - binding cassette sub - family B member 4; P - glycoprotein 3 |
|
Gene ID (Human) |
5244 |
|
Gene ID (Mouse) |
18670 |
|
Protein ID (Human) |
P21439 |
|
Protein ID (Mouse) |
P21440 |
Data
Western blot analysis of ABCB4/MDR3 expression in mouse brain (A) whole cell lysates. (Predicted band size: 135; 140; 141 kD; Observed band size: 144 kD)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
New Products
