ACE2 Rabbit Monoclonal Antibody(ARB867)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6659
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Product Details
Background
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity. Acts as a receptor for SARS coronavirus/SARS-CoV. Acts as a receptor for Human coronavirus NL63/HCoV-NL63.
Overview
| Target | ACE2 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 92 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | Q9BYF1 |
| Immunogen | Synthetic peptide within Human ACE2 aa 750-850 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Membrane & Secreted |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), RT for 30 min |
Data
Immunohistochemical staining of human small intestinal tissue sections for ACE2 using ACE2 Rabbit Monoclonal Antibody (ARB867).
Immunohistochemical staining of human testicular tissue sections for ACE2 using ACE2 Rabbit Monoclonal Antibody (ARB867).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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