Actin, Muscle Specific Mouse Monoclonal Antibody(ARM918)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6708
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Actin is part of the cytoskeletal system of every cell type. It can be classified based on isoelectric points as alpha, beta, and gamma. Muscle Specific Actin includes those of the alpha and gamma isotypes. Skeletal, smooth, and cardiac muscle cells will all stain positively with Anti-Muscle Specific Actin, but mesenchymal cells, not including myoepithelium, will stain negatively. Normal and neoplastic non-muscle cells, including vascular endothelial and connective tissues, carcinomas, melanomas, and lymphomas, will also be negative for muscle specific actin. The use of Anti-Muscle Specific Actin in concert with Anti-Smooth Muscle Actin can allow for differentiation between rhabdomyosarcoma and leiomyosarcoma, as muscle specific actin is found in rhabdomyoblasts, while smooth muscle actin is found in leiomyosarcomas.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50- 1:200 |
Overview
|
Molecular Weight |
42,051 Da |
|
Chromosome Location |
Chromosome: 1; NC_000001.10 (229566992..229569843, complement). Location: 1q42.13 |
|
3D Structure |
ModBase 3D Structure for P68133 |
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Isotype |
IgG1 |
|
Host |
Mouse |
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Species Reactivity |
Human |
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Specificity |
Actin, Muscle Specific |
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Purity/Purification |
Purified |
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Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
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Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human heart tissue using Actin, Muscle Specific Mouse Monoclonal Antibody (ARM918).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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