alpha Glucosidase Activity Assay Kit (Colorimetric)
CAT.NO. : ARG82166
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概述
| 产品描述 | ARG82166 alpha Glucosidase Activity Assay Kit (Colorimetric) can be used to measure alpha Glucosidase activity in biological samples. |
|---|---|
| 反应物种 | Hu, Ms, Rat, All |
| 应用 | FuncSt |
| 靶点名称 | alpha Glucosidase |
| 偶联标记说明 | Read at 405 nm |
| 灵敏度 | 2 U/L |
| 检测范围 | 2 - 250 U/L |
| 样品类型 | biological samples |
| 样本量 | 20 µl |
| 別名 | Lysosomal alpha-glucosidase; LYAG; Aglucosidase alfa; Acid maltase; EC 3.2.1.20 |
应用说明
| 应用说明 | Please note that this kit does not include a microplate. |
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| 检测时间 | 20 min |
属性
| 形式 | Liquid |
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| 存放说明 | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GAA |
| 全名 | glucosidase, alpha; acid |
| 背景介绍 | This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Essential for the degradation of glygogen to glucose in lysosomes. [UniProt] |
| 细胞定位 | Lysosome. Lysosome membrane. [UniProt] |
| 翻译后修饰 | The different forms of acid glucosidase are obtained by proteolytic processing. Phosphorylation of mannose residues ensures efficient transport of the enzyme to the lysosomes via the mannose 6-phosphate receptor. [UniProt] |
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