anti-14-3-3 epsilon antibody [4F8]

CAT.NO. : ARG57090

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [4F8] recognizes 14-3-3 epsilon
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	4F8
同位型	IgG2b, kappa
靶点名称	14-3-3 epsilon
抗原物种	Human
抗原	Recombinant fragment around aa. 1-255 of Human 14-3-3 epsilon
偶联标记	Un-conjugated
別名	KCIP-1; HEL2; MDCR; 14-3-3 protein epsilon; 14-3-3E; MDS

应用说明

应用建议

应用	推荐稀释比
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7531 Human YWHAE Swiss-port # P62258 Human 14-3-3 protein epsilon
基因名称	YWHAE
全名	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
背景介绍	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
生物功能	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. [UniProt]
预测分子量	29 kDa

检测图片 (2)

ARG57090 anti-14-3-3 epsilon antibody [4F8] WB image
Western blot: 40 µg of 1) HeLa, 2) Jurkat, 3) 293T, 4) A549, and 5) Mouse Brain Tissue lysate stained with ARG57090 anti-14-3-3 epsilon antibody [4F8] at 1:1000.
ARG57090 anti-14-3-3 epsilon antibody [4F8] WB image
Western blot: 50 ng of 1) 14-3-3 Zeta, 2) 14-3-3 Beta, 3) 14-3-3 Epsilon, 4) 14-3-3 Eta, 5) 14-3-3 Gamma, 6) 14-3-3 Sigma, and 7) 14-3-3 Tau recombinant proteins stained with ARG57090 anti-14-3-3 epsilon antibody [4F8] at 1:1000.

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