anti-14-3-3 (pan) antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes 14-3-3 (pan)
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: 14-3-3 (pan)
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human 14-3-3.
  • Brand:
CAT.NO. : ARG41068
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes 14-3-3 (pan)
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称14-3-3 (pan)
抗原物种Human
抗原Synthetic peptide derived from Human 14-3-3.
偶联标记Un-conjugated
別名14-3-3; Protein HS1; 1C5; HS1; 14-3-3 protein theta; 14-3-3 protein tau; 14-3-3 protein T-cell
应用说明
应用建议
应用推荐稀释比
WB1:5000 - 1:20000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10971 Human YWHAQ

GeneID: 22630 Mouse YWHAQ

GeneID: 25577 Rat YWHAQ

基因名称YWHAQ
全名tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
背景介绍This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
生物功能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. [UniProt]
细胞定位Cytoplasm. Note=In neurons, axonally transported to the nerve terminals. [UniProt]
预测分子量28 kDa
翻译后修饰Ser-232 is probably phosphorylated by CK1. [UniProt]
检测图片 (1)
  • ARG41068 anti-14-3-3 (pan) antibody WB image

    Western blot: HeLa cell lysate stained with ARG41068 anti-14-3-3 (pan) antibody.

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