anti-ABCF1 / ABC50 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ABCF1 / ABC50
  • 反应物种: Hu
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ABCF1 / ABC50
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human ABCF1.
  • Brand:
CAT.NO. : ARG40299
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ABCF1 / ABC50
反应物种Hu
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ABCF1 / ABC50
抗原物种Human
抗原Synthetic peptide derived from Human ABCF1.
偶联标记Un-conjugated
別名TNF-alpha-stimulated ABC protein; ATP-binding cassette sub-family F member 1; ABC50; ABC27; ATP-binding cassette 50
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:100
IHC-P1:50 - 1:100
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照K562
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4),0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23 Human ABCF1

Swiss-port # Q8NE71 Human ATP-binding cassette sub-family F member 1

基因名称ABCF1
全名ATP-binding cassette, sub-family F (GCN20), member 1
背景介绍The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]
生物功能Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. [UniProt]
细胞定位Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope. [UniProt]
预测分子量96 kDa
翻译后修饰Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. [UniProt]
检测图片 (2)
  • ARG40299 anti-ABCF1 / ABC50 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon stained with ARG40299 anti-ABCF1 / ABC50 antibody.

  • ARG40299 anti-ABCF1 / ABC50 antibody WB image

    Western blot: K562 cell lysate stained with ARG40299 anti-ABCF1 / ABC50 antibody.

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