anti-ABR antibody
| 产品描述 | Rabbit Polyclonal antibody recognizes ABR |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ABR |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 370-407 of Human ABR. (HPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERL) |
| 偶联标记 | Un-conjugated |
| 別名 | MDB; Active breakpoint cluster region-related protein |
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q12979 Human Active breakpoint cluster region-related protein Swiss-port # Q5SSL4 Mouse Active breakpoint cluster region-related protein |
|---|---|
| 基因名称 | ABR |
| 全名 | active BCR-related |
| 背景介绍 | This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012] |
| 生物功能 | GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. [UniProt] |
| 预测分子量 | 98 kDa |
ARG58222 anti-ABR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG58222 anti-ABR antibody at 1 µg/ml dilution.
ARG58222 anti-ABR antibody WB image
Western blot: Rat brain and Mouse brain extracts stained with ARG58222 anti-ABR antibody at 0.5 µg/ml dilution.
ARG58222 anti-ABR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG58222 anti-ABR antibody at 1 µg/ml dilution.
ARG58222 anti-ABR antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human mammary cancer stained with ARG58222 anti-ABR antibody at 1 ug/mL dilution.
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