anti-ACAT1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG54705
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ACAT1 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Mk |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ACAT1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 296-329 (C-terminus) of Human ACAT1 (NP_000010.1). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.3.1.9; Acetoacetyl-CoA thiolase; MAT; T2; ACAT; THIL; Acetyl-CoA acetyltransferase, mitochondrial |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
|---|---|
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P24752 Human Acetyl-CoA acetyltransferase, mitochondrial Swiss-port # Q8QZT1 Mouse Acetyl-CoA acetyltransferase, mitochondrial |
|---|---|
| 基因名称 | ACAT1 |
| 全名 | acetyl-CoA acetyltransferase 1 |
| 背景介绍 | This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009] |
| 生物功能 | Plays a major role in ketone body metabolism. [From Uniprot] |
| 细胞定位 | Mitochondrion. |
| 产品亮点 | Related products: ACAT1 antibodies; Anti-Rabbit IgG secondary antibodies; Related news: Cholesterol, the weakness of anaplastic large cell lymphoma (ALCL) |
| 研究领域 | Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Succinylation at Lys-268, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5 (By similarity). |
检测图片 (2)
ARG54705 anti-ACAT1 antibody WB image
Western blot: 30 µg of 1) HepG2, 2) SW480, 3) 293T, 4) MDAMB231, and 5) MEF lysate stained with ARG54705 anti-ACAT1 antibody at 1:500 dilution.
ARG54705 anti-ACAT1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human hepatocarcinoma tissue stained with ARG54705 anti-ACAT1 antibody.
参考文献
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