anti-ADCY6 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ADCY6
  • 反应物种: Hu, Ms, Rat
  • 应用: Confocal, ELISA, ICC/IF, IHC, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ADCY6
  • 抗原物种: Rat
  • 抗原: KLH-conjugated synthetic peptide around aa. 13-27 of Rat ADCY6. (DERKTAWGERNGQKR)
  • Brand:
CAT.NO. : ARG10772
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ADCY6
反应物种Hu, Ms, Rat
应用Confocal, ELISA, ICC/IF, IHC, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ADCY6
抗原物种Rat
抗原KLH-conjugated synthetic peptide around aa. 13-27 of Rat ADCY6. (DERKTAWGERNGQKR)
偶联标记Un-conjugated
別名Ca; LCCS8; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; AC6; Adenylate cyclase type 6; EC 4.6.1.1; Adenylyl cyclase 6; 2+
应用说明
应用建议
应用推荐稀释比
Confocal1:100 - 1:200
ELISA1:10000
ICC/IF1:100 - 1:200
IHC1:100 - 1:200
IPAssay-dependent
WB1:500
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂30% Glycerol and 0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 112 Human ADCY6

GeneID: 11512 Mouse ADCY6

GeneID: 25289 Rat ADCY6

基因名称Adcy6
全名adenylate cyclase 6
背景介绍This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015]
生物功能Membrane-bound, calcium-inhibitable adenylyl cyclase. [UniProt]
预测分子量131 kDa
翻译后修饰Phosphorylation by RAF1 increases enzyme activity. Phosphorylation by PKA at Ser-662 inhibits the GNAS-mediated increase in catalytic activity. Phosphorylation by PKC at Ser-556, Ser-662 and Thr-919 inhibits catalytic activity.
检测图片 (3)
  • ARG10772 anti-ADCY6 antibody IHC image

    Immunohistochemistry: Rat heart tissue section stained with ARG10772 anti-ADCY6 antibody at 1:100 dilution.

  • ARG10772 anti-ADCY6 antibody WB image

    Western blot: Recombinant ADCY6 protein stained with ARG10772 anti-ADCY6 antibody at 1:500 dilution.

  • ARG10772 anti-ADCY6 antibody IHC image

    Immunohistochemistry: Rat heart tissue section stained with ARG10772 anti-ADCY6 antibody at 1:100 dilution.

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