anti-ADI1 antibody [27E8]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [27E8] recognizes ADI1
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 27E8
  • 同位型: IgG1, kappa
  • 靶点名称: ADI1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57017
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Product Details
概述
产品描述Mouse Monoclonal antibody [27E8] recognizes ADI1
反应物种Hu
应用WB
宿主Mouse
克隆Monoclonal
克隆号27E8
同位型IgG1, kappa
靶点名称ADI1
抗原物种Human
抗原Recombinant fragment around aa. 1-179 of Human ADI1.
偶联标记Un-conjugated
別名1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; mtnD; SIPL; Fe-ARD; APL1; MTCBP1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; Sip-L; EC 1.13.11.54; Submergence-induced protein-like factor; MTCBP-1; ARD; Fe; 2+; Acireductone dioxygenase; Ni-ARD; HMFT1638
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:5000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 55256 Human ADI1

Swiss-port # Q9BV57 Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

基因名称ADI1
全名acireductone dioxygenase 1
背景介绍This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
生物功能Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. [UniProt]
预测分子量21 kDa
检测图片 (1)
  • ARG57017 anti-ADI1 antibody [27E8] WB image

    Western blot: 40 µg of HepG2 cell lysate stained with ARG57017 anti-ADI1 antibody [27E8] at 1) 1:500, 2) 1:1000, and, 3) 1:5000 dilution.

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