anti-ADNP antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ADNP
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ADNP
  • 抗原物种: Human
  • 抗原: Synthetic peptide
  • Brand:
CAT.NO. : ARG44303
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ADNP
反应物种Hu
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ADNP
抗原物种Human
抗原Synthetic peptide
偶联标记Un-conjugated
別名ADNP; Activity Dependent Neuroprotector Homeobox; ADNP1; Activity-Dependent Neuroprotective Protein; KIAA0784; Activity-Dependent Neuroprotector Homeobox Protein
应用说明
应用建议
应用推荐稀释比
WB1:500-1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Antigen Affinity Purified
缓冲液PBS with 0.02% Sodium azide
抗菌剂0.02% Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 23394 Human ADNP

Swiss-port # Q9H2P0 Human Activity-dependent neuroprotector homeobox protein

基因名称ADNP
全名Activity Dependent Neuroprotector Homeobox
背景介绍Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
生物功能May be involved in transcriptional regulation. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation. Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1. May be required for neural induction and neuronal differentiation. May be involved in erythroid differentiation.
细胞定位Chromosome, Nucleus
预测分子量124 kDa
翻译后修饰Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation
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