anti-AGPS antibody [AGPS-03]
![anti-AGPS antibody [AGPS-03]](/upload/image/products/AGPS-03_1_210_205.jpg)
![anti-AGPS antibody [AGPS-03]](/upload/image/products/AGPS-03_1.jpg)
Key features and details
- 产品描述:
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- 应用:
- 特异性:
- 宿主:
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- 靶点名称:
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Brand:
CAT.NO. : ARG65405
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [AGPS-03] recognizes AGPS |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 特异性 | The clone AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | AGPS-03 |
| 同位型 | IgG2a |
| 靶点名称 | AGPS |
| 抗原物种 | Human |
| 抗原 | recombinant human AGPS (amino acids 158-384) |
| 偶联标记 | Un-conjugated |
| 別名 | ADHAPS; ALDHPSY; EC 2.5.1.26; ADAS; ADAP-S; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkyl-DHAP synthase; Alkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from cell culture supernatant by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O00116 Human Alkyldihydroxyacetonephosphate synthase, peroxisomal |
|---|---|
| 基因名称 | AGPS |
| 全名 | alkylglycerone phosphate synthase |
| 背景介绍 | AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse. |
| 生物功能 | Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. [UniProt] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 73 kDa |
检测图片 (1)
ARG65405 anti-AGPS antibody [AGPS-03] WB image
Western blot: HEK293 cell lysate stained with ARG65405 anti-AGPS antibody [AGPS-03].
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