anti-AGR2 + AGR3 antibody [AGR3.4]

产品描述: Mouse Monoclonal antibody [AGR3.4] recognizes AGR2 + AGR3
反应物种: Hu
应用: ICC/IF, IHC-P, WB
特异性: The clone AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
宿主: Mouse
克隆: Monoclonal
克隆号: AGR3.4
同位型: IgG1
靶点名称: AGR2 + AGR3

CAT.NO. : ARG53742

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [AGR3.4] recognizes AGR2 + AGR3
反应物种	Hu
应用	ICC/IF, IHC-P, WB
特异性	The clone AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
宿主	Mouse
克隆	Monoclonal
克隆号	AGR3.4
同位型	IgG1
靶点名称	AGR2 + AGR3
抗原物种	Human
抗原	Purified human AGR3 protein
偶联标记	Un-conjugated
別名	Anterior gradient protein 2 homolog; Secreted cement gland protein XAG-2 homolog; hAG-2; GOB-4; HAG-2; HPC8; PDIA17; HEL-S-116; AG-2; XAG-2; AG2

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

阳性对照

WB and ICC/IF: Positive control: T47D. Negative control: H1299
IHC-P: Positive control: Human colon

属性

形式	Liquid
纯化	Purified from ascites by protein-A affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10551 Human AGR2 Swiss-port # O95994 Human Anterior gradient protein 2 homolog
基因名称	AGR2
全名	anterior gradient 2
背景介绍	AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.
生物功能	Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. [UniProt]
研究领域	Cancer antibody; Signaling Transduction antibody
预测分子量	20 kDa

检测图片 (2)

ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4] WB image
Western blot: 1) H1229 cell lysate, and 2) T47D cell lysate stained with ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4].
ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4] IHC-P image
Immunohistochemistry: Human colon (paraffin sections) stained with ARG53742 anti-AGR2 + AGR3 antibody [AGR3.4].

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