anti-AGR3 antibody [AGR3.1]
CAT.NO. : ARG53743
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概述
产品描述 | Mouse Monoclonal antibody [AGR3.1] recognizes AGR3 |
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反应物种 | Hu |
应用 | ICC/IF, IHC-Fr, IHC-P, WB |
特异性 | The clone AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa); a secreted cytoplasmic protein which can serve as a marker of carcinogenesis. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | AGR3.1 |
同位型 | IgG1 |
靶点名称 | AGR3 |
抗原物种 | Human |
抗原 | Purified human AGR3 protein |
偶联标记 | Un-conjugated |
別名 | Anterior gradient protein 3 homolog; hAG-3; BCMP11; HAG3; AG-3; Breast cancer membrane protein 11; AG3; PDIA18 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
阳性对照 | WB and ICC/IF: Positive control: T47D. Negative control: H1299 IHC-P and IHC-Fr: Positive tissue: breast cancer |
属性
形式 | Liquid |
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纯化 | Purified from ascites by protein-A affinity chromatography. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
抗菌剂 | 15 mM Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | AGR3 |
全名 | anterior gradient 3 |
背景介绍 | AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development. |
研究领域 | Cancer antibody |
预测分子量 | 19 kDa |
检测图片 (2)
ARG53743 anti-AGR3 antibody [AGR3.1] WB image
Western blot: 1. H1229 cell lysate, 2. T47D cell lysate stained with ARG53743 anti-AGR3 antibody [AGR3.1].
ARG53743 anti-AGR3 antibody [AGR3.1] IHC-P image
Immunohistochemistry: Paraffin-embedded sections of breast carcinoma stained with ARG53743 anti-AGR3 antibody [AGR3.1].
