anti-AGTR1 / AT1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes AGTR1
  • 反应物种: Hu, Ms
  • 预测物种: Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: AGTR1 / AT1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG55895
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes AGTR1
反应物种Hu, Ms
预测物种Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称AGTR1 / AT1
抗原物种Human
抗原Synthetic peptide (16 aa) within aa. 210-260 of Human AGTR1.
偶联标记Un-conjugated
別名AT1AR; Angiotensin II type-1 receptor; AT1R; Type-1 angiotensin II receptor; AT1BR; AG2S; AT2R1; HAT1R; AT1; AGTR1B; AT1B
应用说明
应用建议
应用推荐稀释比
ICC/IF20 µg/ml
IHC-P2.5 µg/ml
WB1 - 2 µg/ml
应用说明The dilutions for rat samples might have to be optimized by end user.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse kidney tissue lysate
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 185 Human AGTR1

Swiss-port # P30556 Human Type-1 angiotensin II receptor

基因名称AGTR1
全名angiotensin II receptor, type 1
背景介绍Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
生物功能Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. [UniProt]
预测分子量41 kDa
翻译后修饰C-terminal Ser or Thr residues may be phosphorylated.
检测图片 (4)
  • ARG55895 anti-AGTR1 / AT1 antibody WB image

    Western blot: Mouse kidney tissue lysate stained with ARG55895 anti-AGTR1 / AT1 antibody at (A) 1 and (B) 2 µg/ml dilution.

  • ARG55895 anti-AGTR1 / AT1 antibody IHC-P image

    Immunohistochemistry: Mouse kidney tissue stained with ARG55895 anti-AGTR1 / AT1 antibody at 2.5 µg/ml dilution.

  • ARG55895 anti-AGTR1 / AT1 antibody IF image

    Immunofluorescence: Mouse Kidney cells stained with ARG55895 anti-AGTR1 / AT1 antibody at 20 µg/ml dilution.

  • ARG55895 anti-AGTR1 / AT1 antibody IHC-P image

    Immunohistochemistry: Mouse kidney tissue stained with ARG55895 anti-AGTR1 / AT1 antibody at 2.5 µg/ml dilution.

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