anti-AK1 antibody [7E9]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [7E9] recognizes AK1
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 7E9
  • 同位型: IgG1, kappa
  • 靶点名称: AK1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57175
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Product Details
概述
产品描述Mouse Monoclonal antibody [7E9] recognizes AK1
反应物种Hu
应用WB
宿主Mouse
克隆Monoclonal
克隆号7E9
同位型IgG1, kappa
靶点名称AK1
抗原物种Human
抗原Recombinant fragment around aa. 1-194 of Human AK1
偶联标记Un-conjugated
別名Myokinase; Adenylate kinase isoenzyme 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; EC 2.7.4.6; HTL-S-58j; EC 2.7.4.3; Adenylate monophosphate kinase; AK 1
应用说明
应用建议
应用推荐稀释比
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 203 Human AK1

Swiss-port # P00568 Human Adenylate kinase isoenzyme 1

基因名称AK1
全名adenylate kinase 1
背景介绍Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]
生物功能Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. [UniProt]
预测分子量22 kDa
检测图片 (1)
  • ARG57175 anti-AK1 antibody [7E9] WB image

    Western blot: 40 µg of 1) HeLa, 2) U87-MG, 3) K562, 4) 293T, 5) HepG2, 6) A549, 7) MCF7, 8) SK-OV-3, and 9) PC3 cell lysates stained with ARG57175 anti-AK1 antibody [7E9] at 1:1000.

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