anti-AKAP8 / AKAP95 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes AKAP8 / AKAP95
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: AKAP8 / AKAP95
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63659
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes AKAP8 / AKAP95
反应物种Hu
预测物种Ms, Rat, Cow
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称AKAP8 / AKAP95
抗原物种Human
抗原DQGYGGYGAWSAG-C
偶联标记Un-conjugated
別名AKAP-8; AKAP95; AKAP 95; A-kinase anchor protein 95 kDa; AKAP-95; A-kinase anchor protein 8
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10270 Human AKAP8

Swiss-port # O43823 Human A-kinase anchor protein 8

背景介绍This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
研究领域Cell Biology and Cellular Response antibody
预测分子量76 kDa
翻译后修饰Phosphorylated on tyrosine residues probably by SRC subfamily protein kinases; multiple phosphorylation is leading to dissociation from nuclear structures implicated in chromatin structural changes.
检测图片 (1)
  • ARG63659 anti-AKAP8 / AKAP95 antibody WB image

    Western Blot: Human Liver lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63659 anti-AKAP8 / AKAP95 antibody at 1 µg/ml dilution.

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