anti-AKR1B1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes AKR1B1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: AKR1B1
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human AKR1B1 (NP_001619.1)
  • Brand:
CAT.NO. : ARG55470
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes AKR1B1
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称AKR1B1
抗原物种Human
抗原Recombinant protein of Human AKR1B1 (NP_001619.1)
偶联标记Un-conjugated
別名Aldo-keto reductase family 1 member B1; Aldose reductase; ALR2; ALDR1; AR; Aldehyde reductase; EC 1.1.1.21; ADR
应用说明
预测反应性说明Rat
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse heart and HepG2
实际分子量~ 36 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 231 Human AKR1B1

GeneID: 24192 Rat AKR1B1

Swiss-port # P07943 Rat Aldose reductase

Swiss-port # P15121 Human Aldose reductase

基因名称AKR1B1
全名aldo-keto reductase family 1, member B1 (aldose reductase)
背景介绍This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
生物功能Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. [UniProt]
研究领域Metabolism antibody; Signaling Transduction antibody
预测分子量36 kDa
检测图片 (1)
  • ARG55470 anti-AKR1B1 antibody WB image

    Western blot: Mouse heart and HepG2 cell lysates stained with ARG55470 anti-AKR1B1 antibody.

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