anti-AKR1C1 antibody [6D10]

CAT.NO. : ARG56997

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [6D10] recognizes AKR1C1
反应物种	Hu
应用	FACS, WB
宿主	Mouse
克隆	Monoclonal
克隆号	6D10
同位型	IgG1, kappa
靶点名称	AKR1C1
抗原物种	Human
抗原	Recombinant fragment around aa. 1-323 of Human AKR1C1.
偶联标记	Un-conjugated
別名	20-alpha-hydroxysteroid dehydrogenase; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC 1.1.1.112; EC 1.1.1.-; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; DD1; HBAB; C9; DD1/DD2; High-affinity hepatic bile acid-binding protein; Indanol dehydrogenase; 20-ALPHA-HSD; Aldo-keto reductase family 1 member C1; DDH1; EC 1.1.1.149; H-37; MBAB; EC 1.3.1.20; DDH; Dihydrodiol dehydrogenase 1/2; HAKRC; 2-ALPHA-HSD

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent
WB	1:1000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1645 Human AKR1C1 Swiss-port # Q04828 Human Aldo-keto reductase family 1 member C1
基因名称	AKR1C1
全名	aldo-keto reductase family 1, member C1
背景介绍	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
生物功能	Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. [UniProt]
预测分子量	37 kDa

检测图片 (2)

ARG56997 anti-AKR1C1 antibody [6D10] FACS image
Flow Cytometry: A431 cell line stained with ARG56997 anti-AKR1C1 antibody [6D10] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG56997 anti-AKR1C1 antibody [6D10] WB image
Western blot: 1) 50 ng of Recombinant Human AKR1C1, 2) 40 µg of HepG2 cell lysate, and 3) 40 µg of Raji cell lysate stained with ARG56997 anti-AKR1C1 antibody [6D10] at 1:1000.

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