anti-ALDH1A3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ALDH1A3
  • 反应物种: Hu, Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ALDH1A3
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide corresponding to aa. 24-51 (N-terminus) of Human ALDH1A3.
  • Brand:
CAT.NO. : ARG54807
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ALDH1A3
反应物种Hu, Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ALDH1A3
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 24-51 (N-terminus) of Human ALDH1A3.
偶联标记Un-conjugated
別名RALDH-3; EC 1.2.1.5; Aldehyde dehydrogenase 6; ALDH6; RALDH3; MCOP8; RalDH3; ALDH1A6; Aldehyde dehydrogenase family 1 member A3; Retinaldehyde dehydrogenase 3
应用说明
应用建议
应用推荐稀释比
IHC-PAssay-dependent
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照293
属性
形式Liquid
纯化This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
缓冲液PBS and 0.09% (W/V) Sodium azide
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 220 Human ALDH1A3

GeneID: 56847 Mouse ALDH1A3

Swiss-port # P47895 Human Aldehyde dehydrogenase family 1 member A3

Swiss-port # Q9JHW9 Mouse Aldehyde dehydrogenase family 1 member A3

基因名称ALDH1A3
全名aldehyde dehydrogenase 1 family, member A3
背景介绍This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
生物功能Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity). [UniProt]
细胞定位Cytoplasm.
研究领域Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
预测分子量56 kDa
检测图片 (2)
  • ARG54807 anti-ALDH1A3 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human kideny tissue stained with ARG54807 anti-ALDH1A3 antibody.

  • ARG54807 anti-ALDH1A3 antibody WB image

    Western blot: 35 µg of 293 cell lysate stained with ARG54807 anti-ALDH1A3 antibody.

参考文献

ALDH1A3 Accelerates Pancreatic Cancer Metastasis by Promoting Glucose Metabolism.

IHC-P / Human

Nie Shuang et al.
Front Oncol.,  (2020)

publication_link

 

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