anti-ALDH5A1 antibody [17F5]

CAT.NO. : ARG57061

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [17F5] recognizes ALDH5A1
反应物种	Hu
应用	ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	17F5
同位型	IgG2a, kappa
靶点名称	ALDH5A1
抗原物种	Human
抗原	Recombinant fragment around aa. 48-535 of Human ALDH5A1.
偶联标记	Un-conjugated
別名	SSDH; SSADH; NAD; +; Aldehyde dehydrogenase family 5 member A1; EC 1.2.1.24; Succinate-semialdehyde dehydrogenase, mitochondrial

应用说明

应用建议

应用	推荐稀释比
ICC/IF	Assay-dependent
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 7915 Human ALDH5A1 Swiss-port # P51649 Human Succinate-semialdehyde dehydrogenase, mitochondrial
基因名称	ALDH5A1
全名	aldehyde dehydrogenase 5 family, member A1
背景介绍	This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
生物功能	Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). [UniProt]
预测分子量	57 kDa

检测图片 (3)

ARG57061 anti-ALDH5A1 antibody [17F5] ICC/IF image
Immunoflorescense: 293T cell line stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57061 anti-ALDH5A1 antibody [17F5] WB image
Western blot: 40 µg of HepG2 cell lysate stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:1000.
ARG57061 anti-ALDH5A1 antibody [17F5] WB image
Western blot: 40 µg of Mouse liver tissue extract stained with ARG57061 anti-ALDH5A1 antibody [17F5] at 1:1000.

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