anti-alpha 1 microglobulin antibody
CAT.NO. : ARG44621
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概述
| 产品描述 | Mouse Monoclonal antibody recognizes alpha 1 microglobulin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | alpha 1 microglobulin |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | AMBP; Alpha-1-Microglobulin/Bikunin Precursor; HCP; Protein HC; IATIL; ITILC; EDC1; HI30; ITIL; UTI; Complex-Forming Glycoprotein Heterogeneous In Charge; Inter-Alpha-Trypsin Inhibitor Light Chain; Growth-Inhibiting Protein 19; Uronic-Acid-Rich Protein; Protein AMBP; Trypstatin; Uristatin; Bikunin; ITI; A1M |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | AMBP |
| 全名 | Alpha-1-Microglobulin/Bikunin Precursor |
| 背景介绍 | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008] |
| 生物功能 | Has a chaperone role in facilitating the correct folding of bikunin in the endoplasmic reticulum compartment. Also inhibits calcium oxalate crystallization. [UniProt] |
| 细胞定位 | Cell membrane, Cytoplasm, Endoplasmic reticulum, Extracellular matrix, Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleus, Secreted. [UniProt] |
| 预测分子量 | 39 kDa |
| 翻译后修饰 | Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Proteoglycan. [UniProt] |
检测图片 (3)
ARG44621 anti-alpha 1 microglobulin antibody IHC-P image
Immunohistochemistry: Human liverstained with ARG44621 anti-alpha 1 microglobulin antibody at 2.5 µg/mL dilution.
ARG44621 anti-alpha 1 microglobulin antibody WB image
Western blot: HepG2 stained with ARG44621 anti-alpha 1 microglobulin antibody at 1 µg/mL dilution.
ARG44621 anti-alpha 1 microglobulin antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44621 anti-alpha 1 microglobulin antibody.
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