anti-alpha 2 Antiplasmin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG64629
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes alpha 2 Antiplasmin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, IHC-P, WB |
| 特异性 | This antibody is expected to recognise both reported isoforms (NP_000925.2; NP_001159393.1). Reported variants represent identical protein (NP_000925.2; NP_001159392.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | alpha 2 Antiplasmin |
| 抗原物种 | Human |
| 抗原 | C-KDFLQSLKGFPRGDK |
| 偶联标记 | Un-conjugated |
| 別名 | Alpha-2-AP; Serpin F2; Alpha-2-PI; Alpha-2-antiplasmin; Alpha-2-plasmin inhibitor; AAP; API; PLI; A2AP; ALPHA-2-P |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SERPINF2 |
| 全名 | serpin family F member 2 |
| 背景介绍 | This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| 生物功能 | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
| 细胞定位 | Secreted. |
| 研究领域 | Cell Biology and Cellular Response antibody; Neuroscience antibody |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
检测图片 (2)
ARG64629 anti-alpha 2 Antiplasmin antibody WB image
Western blot: Human Duodenum lysate (35 µg protein in RIPA buffer) stained with ARG64629 anti-alpha 2 Antiplasmin antibody at 0.1 µg/ml dilution.
ARG64629 anti-alpha 2 Antiplasmin antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Liver. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64629 anti-alpha 2 Antiplasmin antibody at 3.8 µg/ml dilution followed by AP-staining.
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