anti-alpha Fetoprotein antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes alpha Fetoprotein |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | alpha Fetoprotein |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (14 aa) within aa. 340-390 of Human alpha Fetoprotein. |
| 偶联标记 | Un-conjugated |
| 別名 | Alpha-fetoprotein; HPAFP; FETA; Alpha-fetoglobulin; AFPD; Alpha-1-fetoprotein |
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human liver tissue lysate |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
|---|---|
| 基因名称 | AFP |
| 全名 | alpha-fetoprotein |
| 背景介绍 | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [UniProt] |
| 预测分子量 | 69 kDa |
| 翻译后修饰 | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
ARG56134 anti-alpha Fetoprotein antibody WB image
Western blot: 20 µl of HepG2 and Mouse liver lysates stained with ARG56134 anti-alpha Fetoprotein antibody at 1 µg/ml dilution.
ARG56134 anti-alpha Fetoprotein antibody ICC/IF image
Immunofluorescence: Rat liver tissue stained with ARG56134 anti-alpha Fetoprotein antibody at 20 µg/ml dilution.
ARG56134 anti-alpha Fetoprotein antibody IHC-P image
Immunohistochemistry: Mouse liver tissue stained with ARG56134 anti-alpha Fetoprotein antibody at 2.5 µg/ml dilution.
ARG56134 anti-alpha Fetoprotein antibody WB image
Western blot: fetal Human liver tissue lysate stained with ARG56134 anti-alpha Fetoprotein antibody at (A) 1 µg/ml and (B) 2 µg/ml dilution.
ARG56134 anti-alpha Fetoprotein antibody IHC-P image
Immunohistochemistry: Rat liver tissue stained with ARG56134 anti-alpha Fetoprotein antibody at 10 µg/ml dilution.
Chromosome territory reorganization through artificial chromosome fusion is compatible with cell fate determination and mouse development
IHC-P / Mouse
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