anti-alpha Fetoprotein antibody [C3]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [C3] recognizes alpha Fetoprotein
  • 反应物种: Hu
  • 不反应物种: Ms, Rat, Cat, Cow
  • 应用: IHC-P
  • 特异性: AFP antibody [C3] is highly specific and shows no cross-reaction with other oncofetal antigens or serum albumin.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: C3
  • 同位型: IgG2a, kappa
  • Brand:
CAT.NO. : ARG55932
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Product Details
概述
产品描述Mouse Monoclonal antibody [C3] recognizes alpha Fetoprotein
反应物种Hu
不反应物种Ms, Rat, Cat, Cow
应用IHC-P
特异性AFP antibody [C3] is highly specific and shows no cross-reaction with other oncofetal antigens or serum albumin.
宿主Mouse
克隆Monoclonal
克隆号C3
同位型IgG2a, kappa
靶点名称alpha Fetoprotein
抗原物种Human
抗原Alpha fetoprotein purified from serum of a hepatoma patient.
偶联标记Un-conjugated
別名Alpha-fetoprotein; HPAFP; FETA; Alpha-fetoglobulin; AFPD; Alpha-1-fetoprotein
应用说明
应用建议
应用推荐稀释比
IHC-P1 - 2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 174 Human AFP

Swiss-port # P02771 Human Alpha-fetoprotein

基因名称AFP
全名alpha-fetoprotein
背景介绍This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
生物功能Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. [UniProt]
细胞定位Cytoplasmic
预测分子量69 kDa
翻译后修饰Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
Sulfated.
检测图片 (1)
  • ARG55932 anti-alpha Fetoprotein antibody [C3] IHC-P image

    Immunohistochemistry: Human fetal liver stained with ARG55932 anti-alpha Fetoprotein antibody [C3].

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