anti-Annexin A1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Annexin A1
  • 反应物种: Hu, Rat, Mk
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Annexin A1
  • 抗原物种: Human
  • 抗原: Recombinant protein corresponding to A2-N346 of Human Annexin A1.
  • Brand:
CAT.NO. : ARG40206
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Annexin A1
反应物种Hu, Rat, Mk
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Annexin A1
抗原物种Human
抗原Recombinant protein corresponding to A2-N346 of Human Annexin A1.
偶联标记Un-conjugated
別名ANX1; Calpactin II; Phospholipase A2 inhibitory protein; Chromobindin-9; LPC1; Annexin-1; Annexin A1; Lipocortin I; Annexin I; p35; Calpactin-2
应用说明
应用建议
应用推荐稀释比
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
应用说明IHC-P: Antigen Retrieval: By heat mediation.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 25380 Rat ANXA1

GeneID: 301 Human ANXA1

Swiss-port # P04083 Human Annexin A1

Swiss-port # P07150 Rat Annexin A1

基因名称ANXA1
全名annexin A1
背景介绍This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
生物功能Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. [UniProt]
细胞定位Endosome; Nucleus; Plasma membrane; Secreted. [UniProt]
预测分子量39 kDa
翻译后修饰Phosphorylated by protein kinase C, EGFR and TRPM7 (PubMed:2457390, PubMed:15485879). Phosphorylated in response to EGF treatment (PubMed:2532504).

Sumoylated. [UniProt]
检测图片 (5)
  • ARG40206 anti-Annexin A1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human tonsil stained with ARG40206 anti-Annexin A1 antibody.

  • ARG40206 anti-Annexin A1 antibody WB image

    Western blot: 0.5 ng of Recombinant Human Annexin A1 Protein stained with ARG40206 anti-Annexin A1 antibody at 0.5 µg/ml dilution.

  • ARG40206 anti-Annexin A1 antibody WB image

    Western blot: 30 µg of sample under reducing conditions. HeLa, K562, COS-7, A549, PC-3, U2OS, Rat spleen, Rat lung, Rat kidney and C6 whole cell lysates stained with ARG40206 anti-Annexin A1 antibody at 0.5 µg/ml dilution, overnight at 4°C.

  • ARG40206 anti-Annexin A1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat lung stained with ARG40206 anti-Annexin A1 antibody.

  • ARG40206 anti-Annexin A1 antibody WB image

    Western blot: 40 µg of HepG2, MCF-7, U87, PANC, SMMC-7721, SW620, COLO320, A549 and Jurkat whole cell lysates stained with ARG40206 anti-Annexin A1 antibody at 0.5 µg/ml dilution.

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