anti-ANP / Atrial Natriuretic Peptide antibody [23/1]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [23/1] recognizes ANP / Atrial Natriuretic Peptide
  • 反应物种: Hu
  • 应用: IHC-P, RIA
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 23/1
  • 同位型: IgG1
  • 靶点名称: ANP / Atrial Natriuretic Peptide
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG23493
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Product Details
概述
产品描述Mouse Monoclonal antibody [23/1] recognizes ANP / Atrial Natriuretic Peptide
反应物种Hu
应用IHC-P, RIA
宿主Mouse
克隆Monoclonal
克隆号23/1
同位型IgG1
靶点名称ANP / Atrial Natriuretic Peptide
抗原物种Human
抗原Synthetic peptide corresponding to part of the native molecule conjugated to BSA.
偶联标记Un-conjugated
別名CDD; Natriuretic peptides A; ANF; Cardiodilatin; Cardiodilatin-related peptide; Atrial natriuretic peptide; Prepronatriodilatin; ATFB6; CDP; ATRST2; ANP; CDD-ANF; PND
应用说明
应用建议
应用推荐稀释比
IHC-PAssay-dependent
RIAAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 0.1% Sodium azide.
抗菌剂0.1% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4878 Human NPPA

Swiss-port # P01160 Human Natriuretic peptides A

基因名称NPPA
全名natriuretic peptide A
背景介绍The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009]
生物功能Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. [UniProt]
预测分子量16 kDa
翻译后修饰Cleaved by CORIN upon secretion to produce the functional hormone.

Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity. [UniProt]
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