anti-AP3D1 antibody
CAT.NO. : ARG59758
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概述
产品描述 | Rabbit Polyclonal antibody recognizes AP3D1 |
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反应物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | AP3D1 |
抗原物种 | Human |
抗原 | Synthetic peptide around the middle region of Human AP3D1. (within the following region: RHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRALDID) |
偶联标记 | Un-conjugated |
別名 | ADTD; hBLVR; AP-3 complex subunit delta; Adaptor-related protein complex 3 subunit delta-1; AP-3 complex subunit delta-1; Delta-adaptin |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
实际分子量 | ~ 130 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
抗菌剂 | 0.09% (w/v) Sodium azide |
稳定剂 | 2% Sucrose |
浓度 | Batch dependent: 0.5 - 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | AP3D1 |
全名 | adaptor-related protein complex 3, delta 1 subunit |
背景介绍 | The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
生物功能 | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. [UniProt] |
细胞定位 | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt] |
预测分子量 | 130 kDa |
