anti-APC11 antibody
Key features and details
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- 反应物种:
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- 抗原:
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Brand:
CAT.NO. : ARG62361
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes APC11 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | APC11 |
| 抗原物种 | Human |
| 抗原 | A peptide from C-terminus of the human APC11. |
| 抗原表位 | aa 76-84 |
| 偶联标记 | Un-conjugated |
| 別名 | Hepatocellular carcinoma-associated RING finger protein; APC11; Cyclosome subunit 11; Apc11p; HSPC214; Anaphase-promoting complex subunit 11 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa, NIH-3T3 cells. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified Antibody |
| 缓冲液 | 1X PBS and 0.1% Sodium azide |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9CPX9 Mouse Anaphase-promoting complex subunit 11 Swiss-port # Q9NYG5 Human Anaphase-promoting complex subunit 11 |
|---|---|
| 基因名称 | ANAPC11 |
| 全名 | anaphase promoting complex subunit 11 |
| 生物功能 | Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody |
| 预测分子量 | 10 kDa |
| 翻译后修饰 | Auto-ubiquitinated. |
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