anti-Aquaporin 1 antibody [7D11]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [7D11] recognizes Aquaporin 1.Mouse anti Aquaporin 1 antibody, clone 7D11 recognizes an epitope within an extracellular region of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28)Aquaporin 1 is a 28kDa integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kDa in mass.
  • 反应物种: Hu, Ms, Rat
  • 应用: ELISA, FACS, IHC-P, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 7D11
  • 同位型: IgG2b
  • 靶点名称: Aquaporin 1
  • 抗原物种: Rat
  • Brand:
CAT.NO. : ARG23488
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Product Details
概述
产品描述Mouse Monoclonal antibody [7D11] recognizes Aquaporin 1.
Mouse anti Aquaporin 1 antibody, clone 7D11 recognizes an epitope within an extracellular region of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28)Aquaporin 1 is a 28kDa integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kDa in mass.
反应物种Hu, Ms, Rat
应用ELISA, FACS, IHC-P, WB
宿主Mouse
克隆Monoclonal
克隆号7D11
同位型IgG2b
靶点名称Aquaporin 1
抗原物种Rat
抗原Synthetic peptide around aa. 198-208 of Rat Aquaporin 1.
偶联标记Un-conjugated
別名Aquaporin-1; CO; AQP-CHIP; AQP-1; Aquaporin-CHIP; Water channel protein for red blood cells and kidney proximal tubule; CHIP28; Urine water channel
应用说明
应用建议
应用推荐稀释比
ELISA1:1000 - 1:10000
FACSAssay-dependent
IHC-PAssay-dependent
WB1:1000 - 1:2000
应用说明IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS, 0.1% Sodium azide and 0.1% BSA.
抗菌剂0.1% Sodium azide
稳定剂0.1% BSA
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11826 Mouse AQP1

GeneID: 25240 Rat AQP1

GeneID: 358 Human AQP1

基因名称AQP1
全名aquaporin 1 (Colton blood group)
背景介绍Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
生物功能Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. [UniProt]
预测分子量29 kDa
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