anti-Arginase 2 antibody [7F8]

CAT.NO. : ARG57058

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Size:

50 μl

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Product Details

概述

产品描述	Mouse Monoclonal antibody [7F8] recognizes Arginase 2
反应物种	Hu
应用	FACS, WB
宿主	Mouse
克隆	Monoclonal
克隆号	7F8
同位型	IgG1, kappa
靶点名称	Arginase 2
抗原物种	Human
抗原	Recombinant fragment around aa. 23-354 of Human Arginase 2.
偶联标记	Un-conjugated
別名	EC 3.5.3.1; Non-hepatic arginase; Type II arginase; Arginase-2, mitochondrial; Kidney-type arginase

应用说明

应用建议

应用	推荐稀释比
FACS	Assay-dependent
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 384 Human ARG2 Swiss-port # P78540 Human Arginase-2, mitochondrial
基因名称	ARG2
全名	arginase 2
背景介绍	Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
生物功能	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. [UniProt]
预测分子量	39 kDa

检测图片 (2)

ARG57058 anti-Arginase 2 antibody [7F8] FACS image
Flow Cytometry: SW480 cell line stained with ARG57058 anti-Arginase 2 antibody [7F8] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57058 anti-Arginase 2 antibody [7F8] WB image
Western blot: 40 µg of SW480 cell lysate stained with ARG57058 anti-Arginase 2 antibody [7F8] at 1:1000 dilution.

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