anti-ASPP1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43696
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ASPP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ASPP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to Human ASPP1. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Apoptosis-stimulating of p53 protein 1 |
| 別名 | Protein phosphatase 1 regulatory subunit 13B; p53BP2-like; ASPP1; p85; Apoptosis-stimulating of p53 protein 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 120-130 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q96KQ4 Human Apoptosis-stimulating of p53 protein 1 |
|---|---|
| 基因名称 | PPP1R13B |
| 全名 | protein phosphatase 1, regulatory subunit 13B |
| 背景介绍 | This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus [UniProt] |
| 预测分子量 | 120 kDa |
| 翻译后修饰 | Methylation; Phosphoprotein |
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