anti-ATAD3A + ATAD3B antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59971
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATAD3A + ATAD3B |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATAD3A + ATAD3B |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-240 of Human ATAD3A (NP_001164006.1). |
| 偶联标记 | Un-conjugated |
| 別名 | ATPase family AAA domain-containing protein 3A |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse brain | ||||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q925I1 Mouse ATPase family AAA domain-containing protein 3 Swiss-port # Q9NVI7 Human ATPase family AAA domain-containing protein 3A |
|---|---|
| 基因名称 | ATAD3A |
| 全名 | ATPase family, AAA domain containing 3A |
| 背景介绍 | ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008] |
| 生物功能 | Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578). [UniProt] |
| 预测分子量 | 71 kDa |
检测图片 (1)
ARG59971 anti-ATAD3A + ATAD3B antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG59971 anti-ATAD3A + ATAD3B antibody at 1:1000 dilution.
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