anti-ATP11B antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG54646
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATP11B |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATP11B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (19 aa) within aa. 290-340 of Human ATP11B protein. |
| 偶联标记 | Un-conjugated |
| 別名 | ATPIF; Probable phospholipid-transporting ATPase IF; ATPase IR; ATPase class VI type 11B; ATPIR; EC 3.6.3.1; P4-ATPase flippase complex alpha subunit ATP11B |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | K562 Cell Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunogen affinity purified |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9Y2G3 Human Probable phospholipid-transporting ATPase IF |
|---|---|
| 基因名称 | ATP11B |
| 全名 | ATPase, class VI, type 11B |
| 背景介绍 | ATP11B Antibody: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions. |
| 研究领域 | Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 134 kDa |
检测图片 (3)
ARG54646 anti-ATP11B antibody ICC/IF image
Immunocytochemistry: ATP11B in K562 cells stained with ARG54646 anti-ATP11B antibody at 10 μg/ml.
ARG54646 anti-ATP11B antibody ICC/IF image
Immunofluorescence: ATP11B in K562 cells stained with ARG54646 anti-ATP11B antibody at 20 μg/ml.
ARG54646 anti-ATP11B antibody WB image
Western blot: 1) K562 cell tissue lysate without blocking peptide 2) K562 cell tissue lysate with blocking peptide stained with ARG54646 anti-ATP11B antibody.
Lysates/proteins at 15 µg per lane.
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