anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes ATP1B2 / Na+ K+ ATPase beta 2 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Bov, Rb |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATP1B2 / Na+ K+ ATPase beta 2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 115-141 (Center) of Human Na+ K+ ATPase beta 2. |
| 偶联标记 | Un-conjugated |
| 別名 | Sodium/potassium-dependent ATPase subunit beta-2; Sodium/potassium-transporting ATPase subunit beta-2; AMOG; Adhesion molecule in glia; adhesion molecule on glia; AT1B2; ATPB2; ATPB2S; Na+ K+ ATPase beta 2; Na K ATPase beta 2; sodium potassium ATPase beta 2; ATPase Na+ K+ beta 2; ATPase Na K beta 2; ATPase sodium potassium beta 2 |
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human brain |
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # P14231 Mouse Sodium/potassium-transporting ATPase subunit beta-2 Swiss-port # P14415 Human Sodium/potassium-transporting ATPase subunit beta-2 |
|---|---|
| 基因名称 | ATP1B2 |
| 全名 | ATPase, Na+/K+ transporting, beta 2 polypeptide |
| 背景介绍 | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] |
| 生物功能 | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type II membrane protein |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 33 kDa |
ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma stained with ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody.
ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody WB image
Western blot: Human brain lysate stained with ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody at 1:1000 dilution.
ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody FACS image
Flow Cytometry: K562 cells stained with ARG55557 anti-ATP1B2 / Na+ K+ ATPase beta 2 antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with FITC labelled secondary antibody.
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