anti-ATP1B3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ATP1B3
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ATP1B3
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human ATP1B3.
  • Brand:
CAT.NO. : ARG42715
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ATP1B3
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ATP1B3
抗原物种Human
抗原Synthetic peptide derived from Human ATP1B3.
偶联标记Un-conjugated
別名Sodium/potassium-dependent ATPase subunit beta-3; Sodium/potassium-transporting ATPase subunit beta-3; ATPB-3; CD antigen CD298; CD298
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 11933 Mouse ATP1B3

GeneID: 25390 Rat ATP1B3

GeneID: 483 Human ATP1B3

基因名称ATP1B3
全名ATPase, Na+/K+ transporting, beta 3 polypeptide
背景介绍The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]
生物功能This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. [UniProt]
细胞定位Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt]
预测分子量32 kDa
检测图片 (1)
  • ARG42715 anti-ATP1B3 antibody WB image

    Western blot: Mouse brain lysate stained with ARG42715 anti-ATP1B3 antibody.

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