anti-ATRIP antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43111
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ATRIP |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ATRIP |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human ATRIP. |
| 偶联标记 | Un-conjugated |
| 別名 | ATR-interacting protein; ATM and Rad3-related-interacting protein |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | PC-3 | ||||||
| 实际分子量 | ~ 88 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ATRIP |
| 全名 | ATR interacting protein |
| 背景介绍 | This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012] |
| 生物功能 | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. [UniProt] |
| 细胞定位 | Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage. [UniProt] |
| 预测分子量 | 86 kDa |
| 翻译后修饰 | Phosphorylated by ATR. [UniProt] |
检测图片 (1)
ARG43111 anti-ATRIP antibody WB image
Western blot: PC-3 cell lysate stained with ARG43111 anti-ATRIP antibody.
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