anti-AZI2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes AZI2
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: AZI2
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human AZI2.
  • Brand:
CAT.NO. : ARG42991
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes AZI2
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称AZI2
抗原物种Human
抗原Recombinant protein of Human AZI2.
偶联标记Un-conjugated
別名NAP1; TILP; 5-azacytidine-induced protein 2; Nak-associated protein 1; AZ2; NF-kappa-B-activating kinase-associated protein 1
应用说明
应用建议
应用推荐稀释比
ICC/IF1:20
WB1:1000 - 1:5000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照K562
实际分子量~ 44 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
浓度Batch dependent
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 27215 Mouse AZI2

GeneID: 316051 Rat AZI2

GeneID: 64343 Human AZI2

基因名称AZI2
全名5-azacytidine induced 2
背景介绍AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]
生物功能Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1. [UniProt]
细胞定位Cytoplasm. [UniProt]
预测分子量45 kDa
检测图片 (1)
  • ARG42991 anti-AZI2 antibody WB image

    Western blot: K562 cell lysate stained with ARG42991 anti-AZI2 antibody at 1:1000 dilution.

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