anti-B56 beta antibody
CAT.NO. : ARG43927
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概述
产品描述 | Rabbit Polyclonal antibody recognizes B56 beta |
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反应物种 | Hu |
应用 | ELISA, FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | B56 beta |
抗原物种 | Human |
抗原 | Human B56 beta recombinant protein |
表达系统 | E.coli |
偶联标记 | Un-conjugated |
Protein Full name | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform |
別名 | PPP2R5B; Protein Phosphatase 2 Regulatory Subunit B'Beta; B56beta; PR61B; B56B; Serine/Threonine-Protein Phosphatase 2A 56 KDa Regulatory Subunit Beta Isoform; FLJ35411; Serine/Threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Beta Isoform; Protein Phosphatase 2, Regulatory Subunit B (B56), Beta Isoform; Protein Phosphatase 2 Regulatory Subunit B', Beta; PP2A, B Subunit, PR61 Beta Isoform; PP2A, B Subunit, B56 Beta Isoform; PP2A, B Subunit, B' Beta Isoform; PP2A, B Subunit, R5 Beta Isoform; PP2A B Subunit Isoform PR61-Beta; PP2A B Subunit Isoform B56-Beta; PP2A B Subunit Isoform B'-Beta; PP2A B Subunit Isoform R5-Beta |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # Q15173 Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta iso |
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基因名称 | PPP2R5B |
全名 | Protein Phosphatase 2 Regulatory Subunit B'Beta |
背景介绍 | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. |
生物功能 | As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation. |
细胞定位 | Cytoplasm |
预测分子量 | 57 kDa |
翻译后修饰 | Phosphoprotein, Ubl conjugation |
检测图片 (3)
ARG43927 anti-B56 beta antibody WB image
Western blot: A431 stained with ARG43927 anti-B56 beta antibody at 0.5 μg/mL dilution.
ARG43927 anti-B56 beta antibody FACS image
Flow Cytometry: SiHa cells stained with ARG43927 anti-B56 beta antibody (blue) at 1 μg/1x10^6 cells dilution.
ARG43927 anti-B56 beta antibody WB image
Western blot: PC-3 stained with ARG43927 anti-B56 beta antibody at 0.5 μg/mL dilution.
