anti-BAF57 / SMARCE1 antibody
CAT.NO. : ARG63519
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概述
产品描述 | Goat Polyclonal antibody recognizes BAF57 / SMARCE1 |
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反应物种 | Hu |
预测物种 | Ms |
应用 | IHC-P, WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | BAF57 / SMARCE1 |
抗原物种 | Human |
抗原 | C-PPTDPIPEDEKKE |
偶联标记 | Un-conjugated |
別名 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1; BRG1-associated factor 57; BAF57 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q969G3 Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin s |
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背景介绍 | The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008] |
研究领域 | Gene Regulation antibody |
预测分子量 | 47 kDa |
翻译后修饰 | Ubiquitinated by TRIP12, leading to its degradation by the proteasome. Ubiquitination is prevented upon interaction between TRIP12 and SMARCC1. |
检测图片 (2)
ARG63519 anti-BAF57 / SMARCE1 antibody WB image
Western Blot: A) 1). Mock transfection; 2) BAF57 (RC209444) overexpressing HEK293 cell lysate standed with ARG63519 anti-BAF57 / SMARCE1 antibody
ARG63519 anti-BAF57 / SMARCE1 antibody IHC-P image
Immunohistochemistry: In paraffin embedded Human Prostate shows nuclear staining in secretory epithelial cells stained with ARG63519 anti-BAF57 / SMARCE1 antibody Recommended concentration, 3-5µg/ml.
