anti-BAG2 antibody [29E9]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [29E9] recognizes BAG2
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 29E9
  • 同位型: IgG2a, kappa
  • 靶点名称: BAG2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57172
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Product Details
概述
产品描述Mouse Monoclonal antibody [29E9] recognizes BAG2
反应物种Hu
应用WB
宿主Mouse
克隆Monoclonal
克隆号29E9
同位型IgG2a, kappa
靶点名称BAG2
抗原物种Human
抗原Recombinant fragment around aa. 1-211 of Human BAG2
偶联标记Un-conjugated
別名BAG family molecular chaperone regulator 2; dJ417I1.2; Bcl-2-associated athanogene 2; BAG-2
应用说明
应用建议
应用推荐稀释比
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 9532 Human BAG2

Swiss-port # O95816 Human BAG family molecular chaperone regulator 2

基因名称BAG2
全名BCL2-associated athanogene 2
背景介绍BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
生物功能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. [UniProt]
预测分子量24 kDa
检测图片 (1)
  • ARG57172 anti-BAG2 antibody [29E9] WB image

    Western blot: 40 µg of 1) Jurkat, 2) A549, 3) K562, 4) HepG2, and 5) HeLa cell lysates stained with ARG57172 anti-BAG2 antibody [29E9] at 1:1000.

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