anti-BAIAP2L1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Rabbit Polyclonal antibody recognizes BAIAP2L1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | BAIAP2L1 |
| 抗原物种 | Human |
| 抗原 | Fusion protein of Human BAIAP2L1. |
| 偶联标记 | Un-conjugated |
| 別名 | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; IRTKS; BAI1-associated protein 2-like protein 1; Insulin receptor tyrosine kinase substrate |
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | WB: HepG2, HeLa, A172, A549 and A431. IHC-P: Human esophagus cancer and human thyroid cancer. |
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | Swiss-port # Q9UHR4 Human Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein |
|---|---|
| 基因名称 | BAIAP2L1 |
| 全名 | BAI1-associated protein 2-like 1 |
| 背景介绍 | This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009] |
| 生物功能 | May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Note=Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine in response to insulin. [UniProt] |
ARG40157 anti-BAIAP2L1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human esophagus cancer stained with ARG40157 anti-BAIAP2L1 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200).
ARG40157 anti-BAIAP2L1 antibody WB image
Western blot: 40 µg of HepG2, HeLa, A172, A549 and A431 cell lysates stained with ARG40157 anti-BAIAP2L1 antibody at 1:800 dilution.
ARG40157 anti-BAIAP2L1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer stained with ARG40157 anti-BAIAP2L1 antibody (left) at 1:30 dilution, or the same antibody pre-incubated with antigen (right). (Original magnification: X200).
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