anti-BCAP31 / BAP31 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes BCAP31 / BAP31
  • 反应物种: Hu, Rat
  • 预测物种: Ms
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: BCAP31 / BAP31
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG55412
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes BCAP31 / BAP31
反应物种Hu, Rat
预测物种Ms
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称BCAP31 / BAP31
抗原物种Human
抗原Synthetic peptide (17 aa) within the last 50 aa of Human BCAP31.
偶联标记Un-conjugated
別名BAP31; Bap31; 6C6-AG; DXS1357E; CDM; BCR-associated protein 31; 6C6-AG tumor-associated antigen; p28; Protein CDM; B-cell receptor-associated protein 31; DDCH
应用说明
应用建议
应用推荐稀释比
IHC-P2 μg/ml
WB0.5 - 2 μg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Ramos Cell Lysate
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10134 Human BCAP31

Swiss-port # P51572 Human B-cell receptor-associated protein 31

基因名称BCAP31
全名B-cell receptor-associated protein 31
背景介绍This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
生物功能Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis. [UniProt]
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量28 kDa
翻译后修饰Cleaved by CASP8 and other caspases.
检测图片 (2)
  • ARG55412 anti-BCAP31 / BAP31 antibody WB image

    Western blot: Ramos cell lysate stained with ARG55412 anti-BCAP31 / BAP31 antibody.

  • ARG55412 anti-BCAP31 / BAP31 antibody IHC image

    Immunohistochemistry: Rat lung tissue stained with ARG55412 anti-BCAP31 / BAP31 antibody at 2 µg/ml dilution.

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