anti-BCAR3 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes BCAR3
  • 反应物种: Ms
  • 预测物种: Hu, Cow, Dog, Pig
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: BCAR3
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63315
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes BCAR3
反应物种Ms
预测物种Hu, Cow, Dog, Pig
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称BCAR3
抗原物种Human
抗原C-RKLEPPPVKQAEL
偶联标记Un-conjugated
別名SH2 domain-containing protein 3B; Novel SH2-containing protein 2; Breast cancer anti-estrogen resistance protein 3; SH2D3B; NSP2
应用说明
应用建议
应用推荐稀释比
WB0.5 - 2 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 29815 Mouse BCAR3

Swiss-port # Q9QZK2 Mouse Breast cancer anti-estrogen resistance protein 3

背景介绍Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
研究领域Controls and Markers antibody
预测分子量93 kDa
检测图片 (1)
  • ARG63315 anti-BCAR3 antibody WB image

    Western Blot: Mouse Kidney epithelial cells lysate (15µg protein in RIPA buffer) stained with ARG63315 anti-BCAR3 antibody at 0.5 µg/ml dilution.

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