anti-BCAT1 antibody [3C8]
![anti-BCAT1 antibody [3C8]](/upload/image/products/ARG57047_WB_1_210_205.jpg)
![anti-BCAT1 antibody [3C8]](/upload/image/products/ARG57047_WB_1.jpg)
Key features and details
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CAT.NO. : ARG57047
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [3C8] recognizes BCAT1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 3C8 |
| 同位型 | IgG1, kappa |
| 靶点名称 | BCAT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-386 of Human BCAT1. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.6.1.42; c; BCT1; ECA39; PP18; Branched-chain-amino-acid aminotransferase, cytosolic; PNAS121; MECA39; Protein ECA39; BCAT; BCATC |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P54687 Human Branched-chain-amino-acid aminotransferase, cytosolic |
|---|---|
| 基因名称 | BCAT1 |
| 全名 | branched chain amino-acid transaminase 1, cytosolic |
| 背景介绍 | This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] |
| 生物功能 | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (1)
ARG57047 anti-BCAT1 antibody [3C8] WB image
Western blot: 40 µg of 1) Jurkat cell lysate, 2) HeLa cell lysate stained with ARG57047 anti-BCAT1 antibody [3C8] at 1:1000.
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