anti-Bcl 11A antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG43692
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Bcl 11A |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Bcl 11A |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment corresponding to BCL11A. |
| 偶联标记 | Un-conjugated |
| Protein Full name | B-cell lymphoma/leukemia 11A |
| 別名 | BCL11A-S; Zinc finger protein 856; BCL11A-XL; HBFQTL5; COUP-TF-interacting protein 1; CTIP1; B-cell lymphoma/leukemia 11A; Ecotropic viral integration site 9 protein homolog; EVI-9; ZNF856; BCL-11A; B-cell CLL/lymphoma 11A; EVI9; BCL11a-M; BCL11A-L |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Ramos | ||||||||
| 实际分子量 | ~ 100 - 145 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BCL11A |
| 全名 | B-cell CLL/lymphoma 11A (zinc finger protein) |
| 背景介绍 | This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity). [UniProt] |
| 预测分子量 | 91 kDa |
| 翻译后修饰 | Sumoylated with SUMO1. [UniProt] |
检测图片 (1)
ARG43692 anti-Bcl 11A antibody WB image
Western blot: Ramos and Raji cells lysates stained with ARG43692 anti-Bcl 11A antibody at 1:1000 dilution.
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