anti-Bcl 11B / Ctip2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG56154
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Bcl 11B / Ctip2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Bcl 11B / Ctip2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 307-334 (Center) of Human Bcl 11B / Ctip2. |
| 偶联标记 | Un-conjugated |
| 別名 | ZNF856B; ATL1-gamma; COUP-TF-interacting protein 2; ATL1-delta; hRit1; B-cell lymphoma/leukemia 11B; CTIP2; B-cell CLL/lymphoma 11B; CTIP-2; RIT1; ATL1-beta; ATL1; hRIT1-alpha; BCL-11B; Radiation-induced tumor suppressor gene 1 protein; ATL1-alpha |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Jurkat |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | BCL11B |
| 全名 | B-cell CLL/lymphoma 11B (zinc finger protein) |
| 背景介绍 | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013] |
| 生物功能 | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). [UniProt] |
| 预测分子量 | 96 kDa |
| 翻译后修饰 | Sumoylated with SUMO1. |
检测图片 (1)
ARG56154 anti-Bcl 11B / Ctip2 antibody WB image
Western blot: 20 µg of Jurkat cell lysate stained with ARG56154 anti-Bcl 11B / Ctip2 antibody at 1:16000 dilution.
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