anti-Bcl 2 antibody [10C4]

CAT.NO. : ARG22186

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [10C4] recognizes Bcl 2
反应物种	Ms, Rat
应用	FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB
特异性	Mouse/Rat Bcl-2
宿主	Mouse
克隆	Monoclonal
克隆号	10C4
同位型	IgG1, kappa
靶点名称	Bcl 2
抗原物种	Mouse
抗原	Synthetic peptide around aa. 61-76 of Murine Bcl-2 protein.
偶联标记	Un-conjugated
別名	BCL2; BCL2 Apoptosis Regulator; PPP1R50; Bcl-2; Protein Phosphatase 1, Regulatory Subunit 50; Apoptosis Regulator Bcl-2; B-Cell CLL/Lymphoma 2; BCL2, Apoptosis Regulator

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	BBS (pH 8.2)
浓度	0.1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	BCL2
全名	B cell leukemia/lymphoma 2
背景介绍	This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
生物功能	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. [UniProt]
细胞定位	Cytoplasm, Endoplasmic reticulum, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus. [UniProt]
产品亮点	Related Antibody Duos and Panels: ARG30268 Apoptosis Marker Antibody Duo (Bcl2, Bax) ARG30269 Apoptosis Marker Antibody Duo (Bcl2, Bid) Related products: Bcl-2 antibodies; Bcl-2 Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Lymphoma
研究领域	Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody; Apoptosis Marker antibody
预测分子量	26 kDa
翻译后修饰	Phosphoprotein, Ubl conjugation. [UniProt]

检测图片 (1)

ARG22186 anti-Bcl 2 antibody [10C4] IHC-Fr image
Immunohistochemistry: Rat Braim stained with ARG22186 anti-Bcl 2 antibody [10C4].
Shu Feng et al. Theranostics., (2023) doi: 10.7150/thno.81951, Fig. 3E.

参考文献

High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization

IHC-Fr / Rat

Shu Feng et al.
Theranostics., (2023)