anti-BCMA antibody
CAT.NO. : ARG44016
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes BCMA |
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反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | BCMA |
抗原物种 | Human |
抗原 | Human BCMA recombinantprotein |
偶联标记 | Un-conjugated |
Protein Full name | Tumor necrosis factor receptor superfamily member 17 |
別名 | TNFRSF17; TNF Receptor Superfamily Member 17; BCM; TNFRSF13A; CD269; BCMA; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Protein; Tumor Necrosis Factor Receptor Superfamily, Member 17; B Cell Maturation Antigen; B-Cell Maturation Factor; CD269 Antigen |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | PBS containing 0.02% sodium azide |
抗菌剂 | 0.02% sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17 |
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基因名称 | TNFRSF17 |
全名 | TNF Receptor Superfamily Member 17 |
背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. |
生物功能 | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK |
细胞定位 | Cell membrane, Membrane |
预测分子量 | 20 kDa |
翻译后修饰 | Disulfide bond |
检测图片 (3)
ARG44016 anti-BCMA antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG44016 anti-BCMA antibody at 5 μg/mL dilution.
ARG44016 anti-BCMA antibody WB image
Western blot: Human spleen and K562 stained with ARG44016 anti-BCMA antibody at 5 μg/mL dilution.
ARG44016 anti-BCMA antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG44016 anti-BCMA antibody at 10 μg/mL dilution.
